Searchable abstracts of presentations at key conferences in endocrinology

ea0003p198 | Neuroendocrinology | BES2002

Functional complement C3a receptors in the rat pituitary gland

Lewis B , Francis K , Gasque P , Scanlon M , Ham J

The hypothalamic pituitary adrenal (HPA) axis is the major regulator of stress and inflammation via the secretion of anti-inflammatory corticosteroids. This suggests an important bidirectional flow of information between the endocrine and immune systems. A critical component of the inflammatory response is the complement cascade in which anaphylatoxins C3a, C4a and C5a are released.In this report we used colocalisation immunohistochemistry to show detai...